The chemistry
Peptides are short chains of amino acids linked by peptide bonds. They sit between individual amino acids and full-length proteins in size, typically ranging from two to roughly fifty residues.
In a laboratory context, peptides are characterized by properties such as:
- Amino acid sequence
- Molecular weight
- Net charge and isoelectric point
- Solubility profile
- Purity by HPLC
- Identity by mass spectrometry
How research peptides are produced
Most research peptides are produced by solid-phase peptide synthesis (SPPS), where the chain is assembled one residue at a time on a solid resin support, then cleaved and purified.
Purification is commonly performed by reversed-phase HPLC, and the finished material is lyophilized (freeze-dried) into a stable powder for laboratory storage and shipping.
Reading a Certificate of Analysis
Every batch should be accompanied by analytical documentation. A typical Certificate of Analysis (COA) reports:
- Batch or lot number tied to the specific production run
- Purity percentage determined by HPLC, with the chromatogram
- Identity confirmation by mass spectrometry
- Appearance and physical form of the lyophilized material
- Date of analysis and the testing laboratory
Laboratory handling and storage
General laboratory practice for lyophilized peptide reference material includes storing vials sealed and protected from light, moisture, and repeated temperature cycling.
Materials should be handled only by trained personnel using appropriate personal protective equipment, in accordance with your institution's standard operating procedures and safety policies.
Why documentation matters
Reproducible laboratory work depends on knowing exactly what is in the vial. Batch-specific analytical data lets a researcher verify identity and purity before any experimental work begins.
Atlas US Labs supplies research materials with third-party analytical documentation so that identity and purity can be independently reviewed.
Regulatory status
The research materials offered by Atlas US Labs are not approved by the U.S. Food and Drug Administration for human or veterinary use, and are not drugs, dietary supplements, cosmetics, or medical devices.
Nothing on this site describes methods of administration, dosing, or use in humans or animals, and nothing here should be interpreted as medical advice. Purchasers are responsible for compliance with all applicable federal, state, and local laws.
RESEARCH USE ONLY
All products sold by Atlas US Labs are intended strictly for in-vitro laboratory research by qualified professionals. They are not for human or animal consumption, and are not intended to diagnose, treat, cure, or prevent any disease.